Formoterol dry powder in asthma.

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Formoterol dry powder in asthma.

We read with interest the paper by Douglas and coworkers (July 1993;48,719-21) on the possible inheritance of sleep disturbed breathing. Investigating 40 first degree relatives of patients with sleep apnoeas, they found a high prevalence of sleep apnoeas/ hypopnoeas (25%), several times higher than the prevalence in a random sample of the British population (5%).' The authors concluded that a f...

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Time course and duration of bronchodilatation with formoterol dry powder in patients with stable asthma.

BACKGROUND Formoterol, a new beta 2 agonist, is long and fast acting when given as an aerosol. The aim was to determine the onset and duration of bronchodilatation with formoterol as a dry powder compared with salbutamol dry powder and with placebo. METHODS Fifteen patients with stable asthma with a reversibility of 15% or more participated in a double blind, within patient study. On five dif...

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Fluticasone/formoterol dry powder versus budesonide/formoterol in adults and adolescents with uncontrolled or partly controlled asthma.

UNLABELLED This 12-week study compared the efficacy and safety of a fixed combination of fluticasone propionate plus formoterol (FL/F) 250/12 μg b.i.d. administered via a dry powder inhaler (DPI) (Libbs Farmacêutica, Brazil) to a combination of budesonide plus formoterol (BD/F) 400/12 μg b.i.d. After a 2-week run-in period (in which all patients were treated exclusively with budesonide plus for...

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Flow-dependent effect of formoterol dry-powder inhaled from the Aerolizer.

The output and size distribution of aerosols from dry powder inhalers are dependent on the flow rate through the device. Therefore, in an in vivo study, we examined the flow-dependency of the effect of formoterol when delivered from a dry powder inhaler, the Aerolizer, in a flow range relevant to schoolchildren. In a preliminary study comprising 126 asthmatic children aged 3-10 yrs, the relatio...

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Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma.

The present study was designed to compare the fixed combination of beclomethasone and formoterol in a hydrofluoroalkane Modulite (Chiesi Farmaceutici, Parma, Italy) pressurised metered-dose inhaler (pMDI), with a combination of budesonide and formoterol administered via a Turbuhaler (AstraZeneca, Lund, Sweden) dry powder inhaler (DPI). This was a phase III, multinational, multicentre, double-bl...

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ژورنال

عنوان ژورنال: Thorax

سال: 1994

ISSN: 0040-6376

DOI: 10.1136/thx.49.1.95-a